Gynaecoloog - professor Depypere

Professor Herman Depypere zet zich in voor de gezondheid van de vrouw. Gezond betekent vrij van ziekte. Vaak kunnen ziekten zoals osteoporose, baarmoederkanker, baarmoederhalskanker, dementie, borstkanker worden voorkomen. Door gericht bepaalde testen te verrichten kan deze ziekten, nog voor ze gevaarlijk worden, opsporen en zodoende vermijden. Door ver doorgedreven onderzoeken worden de laatste wetenschappelijk bevindingen toegepast in dit streven naar gezond blijven.

Professor Herman Depypere studeerde af als doctor in de geneeskunde aan de universiteit van Gent in 1986. Vervolgens behaalde hij zijn biomedisch doctoraat met grootste onderscheiding in 1991. Hij werd erkend als gynaecoloog in 1991, na verblijven in het buitenland aan de universiteiten van Rotterdam (Nederland), Adelaide (Australië), Rijsel (Frankrijk), Birmingham (VK). In 1994 behaalde hij zijn PhD thesis.

Professor Depypere is voltijds hoogleraar aan de borst–en menopause kliniek in het universitair ziekenhuis te Gent. Hij heeft een privaat praktijk op de Coupure 4, Gent. Hij is past vice president van de Europese Menopause Vereniging en de huidige president van de Belgische Menopause Vereniging. Zijn expertise overkoepelt de domeinen van behandeling en preventie van borstkanker. Met de universiteit van Philadelphia (USA) en Hasselt werkt hij aan het voorkomen van borstkanker door middel van behandeling met zwangerschapshormoon.

Verder coördineert hij samen met de Sorbonne universiteit een studie die preventie van dementie door middel van toediening van natuurlijke hormonen tot doel heeft. Hij is auteur van twee boeken over gezondheid tijdens de menopause. Hij is auteur van meer dan 300 artikels waarvan de meeste internationale peer reviewed zijn (zie extended curriculum).

CV: Professor Depypere graduated as medical doctor at the University of Ghent in 1986 with great distinction. Subsequently he obtained his biomedical science degree, with greatest distinction in 1991. He became gynaecologist in 1991 after having being registrar at the university hospitals of Ghent (Belgium), Rotterdam (Netherlands), Adelaide (Australia), Lille (France), Birmingham (UK). He is a consultant at the University Hospital of Ghent since 1991.

He obtained a PhD at the University of Ghent in 1994. He is full time Professor at the University Clinic since 1998. He is currently head of clinic of menopause clinic and breast clinic. He is associated professor at the laboratory of experiment oncology. He is past vice president of the European Menopause Society and is the current president of the Belgian Menopause Society.

He published more than 200 publications. He recently published on Alzheimers Dementia prevention with MHT (Alzheimers and Dementia, impact factor 22). He recently published on strategies to prevent breast cancer by prolonged administration of pregnancy hormone in young women (European journal of cancer prevention).

PERSONALIA

Name: DEPYPERE
First name: HERMAN TOM
Date of birth: 28 JULY 1961
Present occupation FULL PROFESSOR
Department: Gynaecology, university Hospital of Ghent
Head of clinic: Breast and menopause clinic
Private practice: Coupure menopause clinic
Coupure 4, 9000 Ghent
E-mail: HERMAN.DEPYPERE@UGENT.BE
Formation: at the universities of Ghent (Belgium), Birmingham (UK), Rotterdam (Holland), Lille (France), Adelaide (Australia)

Clinical studies

Contraception with E4 published
NK3 antagonists in women with vasomotor symptoms published
rhCG in BRCA1 and 2 carriers published
rhCG in BRCA1 and 2 carriers, extension studies 2021- ongoing
Hormone supplementation and cognition Finished recruitment
Hot Flashes in postmenopausal women 2018 – published
Urology and hormone therapy 2018 – published Hormone therapy and nicturia 2018 – ongoing
Endometriosis 2014 – present
Vaginal ring in dysmenorrhea 2013 – 2015
Contraception 2010 – 2014: published
Glucose metabolism in postmenopausal women 2010 – 2014: published
Acquired female sexual dysfunction and contraception 2010 – 2011
Breast cancer 2010 – 2015
Prevention breast cancer in BRCA carriers 2016- ongoing
Influence hormones on dementia 2018- ongoing
Older studies: Breast cancer (BIG 1-98), Atac trial, IBIS trial, Liberate trial

Publications in books
Leybaert L and Depypere HT. In vitro gamete micromanipulation and intracellular ionic changes. In Recent developments in obstetrics and gynecology, Parthenon Publishing Group, 1995, UK

Depypere H, Gerris J, Comhaire F. Donor sperm insemination and spermbanking. In Male Infertility – Clinical Investigation, Cause, Evaluation and Treatment. Ed Comhaire. Chapter 23 Hall Medical, London, 1996.

Comhaire F, Depypere H, Gordts S, Milingos S, Schoonjans F. The effective cumulative pregnancy rate of conventional and advanced methods of treatment of oligo-astheno-terato-zoospermia. In Research in Male gametes : production and quality. Eds Hamamah S, Mieusset R, pp 299-305, 1996.

Bracke M, Boterberg T, Depypere H, Stove Ch, Leclercq G, Vandecasteele, Mareel M. The citrus methoxyflavone tangeretin affects human cell-cell interactions. In : Flavonoids in Cell Function. J.A. Manthley and B. Buslig (Eds.) , Kluwer Academic/Plenum Publishers, New York, 2002, pp 135-139.

B. Vanhoecke, H. Depypere, D. De Keukeleire, and M. Bracke. Cellular activities related to growth and invasion: Targets for flavonoids. Recent Res. Devel. Cell Sci., 1(2004): 165-192. ISBN: 81-7895-112-6. Transworld Research Network.

B.W. Vanhoecke, H.T. Depypere and M. Bracke: Molecular cross-talks during invasion and metastasis. In: Recent Research Developments in Cell Science. S.G. Pandalai (Ed.), Transworld Research Network, Kerala, 2004

L. Derycke, V. Van Marck, H. Depypere and M. Bracke: Cancer, a Disease of Growth, Differentiation, Tissue Integrity and Ectopic Cell Death. In: In vivo Characterisation of Tumors by means of Nuclear Medicine. C. Vandewiele (Ed.), academia press, 2004.

Bracke, M.E., Boterberg, T., Depypere, H.T., Stove, C., Leclercq, G. and Mareel, M.M.:
The citrus methoxyflavone tangeretin affects human cell-cell interactions. In: “Flavonoids in Cell Function”, pp. 135-139 (B. Buslig and J. Manthey, Eds.). Kluwer Academic/Plenum Publishers, New York, 2002.

Bracke, M.E., De Maeseneer, D., Van Marck, V., Derycke, L., Vanhoecke, B., De Wever, O. and Depypere, H.T.: Cell motility and breast cancer metastasis. In: “Breast Cancer Metastasis”, Chapter 4, pp. 47-75 (R.E. Mansel, O. Fodstad and W.G. Jiang, Eds.). Kluwer (Springer) Academic Publishers, 2007.

Depypere Herman: Menopauze alle vragen beantwoord. Currently available (order through website).

Depypere Herman: menopauze menostart: tips en trics. Currently available (order though website)

A1 publications

Luyten F, Verbruggen G, Veys E, Goffin E, Depypere H. In vitro repair potential of articular cartilage proteoglycan metabolism in the different areas of the femoral condyles in human cartilage explants. J Rheumatology 1985;14:329- 334.

Depypere HT, McLaughlin KJ, Seamark RF, Warnes GM, Matthews CD. A comparison of zona cutting and zona drilling as techniques for assisted fertilization in the mouse. J Reprod Fertil 1988;84:205-211.

Carroll J, Depypere HT, Matthews CD. Freeze-thaw induced changes of the zona pellucida explains decreased rates of fertilization in frozen-thawed mouse oocytes. J Reprod Fertil 1990;90:547-553.

Depypere HT, Carroll JC, Vandekerckhove D, Matthews CD. Normal survival and in vitro development after cryopreservation of zona drilled embryos. Human Reproduction 1991;6:432-435.

Payne D, McLaughlin KJ, Depypere HT, Kirby CA, Warnes GM, Matthews CD. Experience with zona drilling and zona cutting to improve fertilization rates of human oocytes in vitro. Human Reproduction 1991;6:423-431.

Depypere HT, Dhont M, Verschraegen-Spae MR, Coppens M. Tubal hydatidiform mole. Am J Obstet Gyn 1993;169:209-210.

Verschraegen-Spae MR, Depypere HT, Speleman F, Dhont M, De Paepe A. Familial Turner syndrome. Clin Genet 1992;41:218-220.

Depypere HT, Leybaert L. Intracellular pH changes during zona drilling. Fertil Steril 1994;61:319-323.

Depypere HT, Gordts S, Campo R, Comhaire F. Methods to increase the success rate of artificial insemination with donor semen. Human Reproduction 1994;9:661-663.

Comhaire F, Depypere HT, Gordts S, Millingos S. Up-to-date management of male infertility : conventional treatment versus assisted reproductive technology. J Fert Reprod 1994;1:6-10.

Depypere HT, Millingos A, Comhaire F. Intrauterine insemination in male subfertility : a comparative study of spermpreparation using a commercial percoll kit and conventional sperm wash. Eur J Obst Gyn and Reprod Biol 1995;62:225-229.

Comhaire F, Depypere H, Millingos S. Statement on intra-uterine insemination. International Journal of Andrology 1995;18:76-77.

Comhaire F, Millingos A, Liapi A, Gordts S, Campo R, Depypere H, Dhont M and Schoonjans F. The effective cumulative pregnancy rate of different modes of treatment of male infertility. Andrologia 1995;27:217-221.

Van Kets H, Vrijens M, Van Trappen Y, Delbarge W, Van de Pas H, Temmerman M, Depypere H, Batar I, Barri P, Martinez F, Iglesias-Cortit L, Wu Shangchun, Hu Jing, Cao Xiaoming, Feng Zuan-chong, Wu Ming Hui, Wildemeersch D, Pizarro E, Andrade A and Thiery M. The frameless GyneFix intrauterine implant : a major improvement in efficacy, expulsion and tolerance. Adv Contracept 1995;11:131-142.

Leybaert L, Depypere H, Dhont M, de Hemptinne A. Changes of intracellular free calcium during intracytoplasmic sperm injection. Molecular Reproduction and development 1996;43:256-260.

Depypere H, Dhont M. Chronic uterovaginal prolapse : preoperative treatment. J of Obstetrics and Gynaecology 1997;17:209-210.

Depypere H, Coppens M, Versichelen L, Serreyn R, Van Kets H, Dhont M. Endometrial spreading during endometrium ablation. Gynaecological Endoscopy 1997;6:155-156.

Van de Voorde, Depypere H, Vanheel B. The influence of pregnancy on endothelium-derived nitric oxide mediated relaxations in isolated human resistance vessels. Fundam Clin Pharmacol 1997;11:371-377.

Bracke M, Depypere H, Labit C, Van Marck V, Vennekens K, Vermeulen S, Mael fait I, Phillipe J, Serreyn R, Mareel M. Functional downregeulation of the E-cadherin/catenin complex leads to loss of contact inhibition of motility and of mitochondrial activity, but not of growth in confluent epithelial cell cultures. European Journal of Cell Biology 1997;74:342-349.

Van Kets H, Van der Pas H, Thiery M, Wildemeersch D, Vrijens M, Vantrappen Y, Temmerman M, Depypere H, Delbarge W, Dhont M et al. The Gynefix implant systems for interval, postabortal and postpartum contraception : a significant advance in long -term reversible contraception. The European Journal of Contraception and Reproductive Health Care 1997;2:1-13.

Wildemeersch D, Van Kets H, Vrijens M, Delbarge W, Vantrappen Y, Temmerman M, Depypere H and Thiery M. Intrauterine contraception in adolescent women : The Gynefix implant. Annals of the New York Academy of Sciences 1997;816:440-450.

Van de Voorde J, Delaey, Ch, Depypere H, Vanheel B. Mechanisms involved in the vasorelaxing influence of histamine on isolated human subcutaneous resitance arteries. Eur J Pharmacol 1998;349:61-66.

Bracke M, Depypere H, Boterberg T, Van marck V, Vennekens K, Vanluchene E, Nuytinck M, Serreyn R, Mareel M. Inhibition of Tamoxifen’s therapeutic benefit by tangeretin in mammary cancer Journal of the National Cancer Institute 1999;91:354-359. Commented by Susan Gilbert in The New York Times : “Surprise Finding on Tamoxifen and Citrus” (2-3-1999). Commented by Valerie Andrews in Healthscout : “Cancer Treatment Jinxed by Juice? Citrus can thwart tamoxifen” (8-4-1999).

Depypere H, Rong H, Boterberg T, Serreyn R, Stove Ch, Van Slambrouck S, De Keukeleire D, Mareel M, Bracke M. 8-Prenylnaringenin, the phytoestrogen in hops and beer, may influence the incidence of breastcancer. Europ. J. Cancer 2000 ; 36: 71-77.

Nickelsen T., Creatsas G., Rechberger T. Depypere H., Erenus M., Quail D., Arndt T., Bonnar J., for the Euralox 1 Study Group. Diffential effects of raloxifene and continuous combined hormone replacement therapy on biochemical markers of cardiovascular risk. Climacteric 2001 ;4 :320-331.

Maubach, J.; Depypere, H.; Serreyn, R.; De Keukeleire, D.; Mareel, M.; Bracke, M.; “Quantitation of soy phytoestrogens in human breast tissue and biological fluids”, J. Nutr., 2002, 132, 577-577.

Rong H, Boterberg T, Maubach J, Stove Ch, Depypere H, Van Slambrouck S, Serreyn R, De Keukeleire D, Mareel M, Bracke M. 8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells. Eur J Cell Biol 2001 ; 80 :580-585.

Herman Depypere, Patrick Neven, Tore Lunde, Pierluigi Benedetti-Panici, Aila Tiitinen, Bodgan Marinescu, Tobie de Villiers, Tim Hillard, Antonio Cano, Eitan Peer, Deborah Quail, Thomas Nickelsen for the Euralox 1 Study Group. Euralox 1: Uterine safety of Kliogest versus Evista: Preliminary results. Europ. J. Cancer 2002, 38, 7.

Depypere HT, De Prins F, De Sutter Ph, Makar A, Schockaert N, Tjalma W, Van Dam P, Vergote I Neven P on behalf of the VWOG. Hormone receptor expression in flemish patients with in situ and invasive primary breastcancer. Europ. J. Cancer 2002. Suppl 6.

Cocquyt V, Villeirs G, Blondeel Ph, Depypere H, Mortier M, Serreyn R, Van Den Broecke R, Van Belle S. Assessment of response to preoperative chemotherapie in patients with stage II and III breast cancer : the value of MRI. The Breast 2002 ;11 :309-315.

Bracke M, Boterberg T, Depypere H, Stove Ch, Leclercq G, Vandecasteele, Mareel M. The citrus methoxyflavone tangeretin affects human cell-cell interactions. In : Flavonoids in Cell Function. J.A. Manthley and B. Buslig (Eds.), Kluwer Academic/Plenum Publishers, New York, 2002, pp 135-139.

Cocquyt V, Blondeel Ph, Depypere H, Praedt M, Schelfhout V, Silva O, Hurley J, Serreyn R, Daems K, Van Belle S. Different responses to preoperative chemotherapy for invasive lobular and invasive ductal breast carcinoma. EJSO 2003 ;29 :361-367.

Selvaggi G, Monstrey S, Depypere H, Blondeel P, Van Landuyt K, Hamdi M, Dhont M.
Creation of a neovagina with use of a pudendal thigh fasciocutaneous flap and restoration of uterovaginal continuity. Fertil Steril. 2003 Sep;80(3):607-11.

Cocquyt V, Blondeel Ph, Depypere H, Van De Sijpe K, Daems K, Monstrey S, Van Belle S. Better cosmetic results and comparable quality of lift after skin-sparing mastectomy and immediate autologous breast reconstruction compared to breast conservative treatment. BJPS 2003 ;56 :462-470.

Maubach J, Bracke M, Heyerick A, Depypere H, Serreyn R, Mareel M, De Keukeleire D. Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography. J Chromotography B 2003 ;784 :137-144.

Cocquyt V, Schelfhout V, Blondeel Ph, Depypere H, Daems K, Serreyn R. The role of biological markers as predictors of response to preoperative chemotherapy in large primary breast cancer. Medical Oncol 2003 ;20 :221-232.

Maubach J, Depypere H, Goeman J, Van der Eycken J, Heyerick A, Bracke M, Blondeel P and De Keukeleire D. Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids. Obstetrics and Gynecology . Obstetr Gynecol 2004; 103, 892-898.

Vanhoecke, B.; Depypere, H.; De Keukeleire, D.; Bracke, M.; “Cellular activities related to growth and invasion: Targets for flavonoids”, Recent Res. Devel. Cell. Sci., 2004, 1, 165-192.

De Coen K., Lissens W., De Cuyper C., Depypere H., De Praeter C. De Coen K., Lissens W., De Cuyper C., Depypere H., De Praeter C. Familial male lethal incontinentia pigmenti: a rare cause of recurring spontaneous abortions. Journal of Maternal-Fetal & Neonatal Medicine 2004, 16 suppl 1, p253.

M.E. Bracke, B.W. Vanhoecke, H.T. Depypere, H.J. Kloosterboer. Tibolone and its metabolites inhibit the invasion of human breast cancer cells. EJC Supplements, 2004, 2(9): 105-112.

Neven P, Quail D, Marin F, Creatsas G, Depypere H, Rechberger T, Liu-Leage S, Pavo I, Schmitt H, Nickelsen T. Comparing raloxifene with continuous combined estrogen-progestin therapy in potmenopausal women: review of Euralox 1. Maturitas 2005; 52: 87-101.

Van Slambrouck S, Parmar V, Sharma S, De Bondt B, Flore F, Coopman P, Vanhoecke B, Boterberg T, Depypere H, Leclercq G, Bracke M. Tangeretine inhibits extracellular-signal-regulated kinase phorphorylation. FEBS Letters, 2005, 579:1665-1669.

Vanhoecke B, Delporte F, Van Braeckel E, Heyerick A, Depypere H, Nuytinck M, De Keukeleire D, and Bracke M. A Safety study of oral tangeretin and xanthohumol administration to laboratory mice. In Vivo, 2005, 19: 103-108.

Vanhoecke B, Depypere H, De Beyter A, Sharma S, Parmar V, De Keukeleire D, and Bracke M. New anti-invasive compounds: results from the Indo-Belgian screening program. Pure Appl. Chem., 2005, 77(1):65-74.

Beerens E, Van Rentergem L, Praet M Sturtewagen Y, Weyers S, Temmerman M, Depypere H, Claeys P, Cuvelier C. Human papillomavirus DNA detection in women with primary abnormal cytology of the cervix : prevalence and distribution of HPV genotypes. Cytopathology 2005 16;199-205.

Derycke L, Van Marck V, Depypere H, Bracke M. Molecular targets of growth, differentiation, tissue integrity and ectopic cell dath in cancer cells. Cancer Biother Radiopharmac. 2005, 20:579-588.

Vanhoecke B, Derycke L, Van Marck V, Depypere H, De Keukeleire D, and Bracke M. The anti-invasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer. Int. J. Cancer 2005, 889-895.

Depypere, H., Bracke, M., Vanhoecke, B., De Keukeleire, D., Heyerick, A., Bolca, S., Verstraete W. Are phytoestrogens of any help? International Journal of Gynecological Cancer, 2006; 16[S2], 580-580.

Heyerick A, Vervacke S, Depypere H, Bracke M, De keukeleire D. A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. Maturitas 2006; 54: 164-175.

Vanhoecke B.W., Bracke M.E, Kloosterboer H.J. en Depypere H.T. Tibolone and its metabolites inhibit invasion of human mammary carcinoma cells in vitro. Maturitas 2006; 54: 229-237.

Depypere HT, Langlois MR, Delanghe JR, Temmerman M, Dhont M. Haptoglobin polymorphism in patients with preeclampsia. Clin Chem Lab Med. 2006;44(8):924-8.

Derycke L, De Wever O, Stove V, Vanhoecke B, Delanghe J, Depypere H, Bracke M. Soluble N-cadherin in human biological fluids. Int J Cancer. 2006 Dec 15;119(12):2895-2900.

Dollé L, Depypere HT, Bracke ME. Anti-invasive/anti-metastasis strategies: new roads, new tools and new hopes. Curr Cancer Drug Targets. 2006 Dec;6(8):729-51.

Depypere H, Ph Tummers, De Bacquer D, Debacker G, Do M, Dhont M. Number of women needed in a prospective trial to prove potential cardiovascular benefit of hormone replacement therapy. Climacteric. 2007 ; 10:238-243.

Possemiers, S., Bolca, S., Eeckhaut, E., Depypere, H., Verstraete, W. Metabolism of isoflavones, lignans and prenylflavonoids by intestinal bacteria: producer phenotyping and relation with intestinal community. FEMS Microbiology Ecology, 2007; 61; 372-383.

Bolca S, Possemiers S, Maervoet V, Huybrechts I, Heyerick A, Vervarcke S, Depypere H, De Keukeleire D, Bracke M, De Henauw S, Verstraete W, Van de Wiele T. Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. Br J Nutr. 2007 Nov;98(5):950-9.

Bolca, S., Possemiers, S., Herregat, A., Huybrechts, I., Heyerick, A., De Vriese, S., Verbruggen, M., Depypere, H., De Keukeleire, D., Bracke, M., De Henauw, S., Verstraete, W., Van de Wiele, T. Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women. Journal of Nutrition, 2007; 137[10], 2242-2246.

De Wever O, Derycke L, Hendrix A, De Meerleer G, Godeau F, Depypere H, Bracke M. Soluble cadherins as cancer biomarkers. Clin Exp Metastasis. 2007;24(8):685-97.

Maubach, J., Bracke, M., Depypere, H., De Keukeleire, D. and Heyerick, A.: Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood, JPCCR, 2, 64-70, 2008.

Sturdee DW, Archer DF, Rakov V, Lang E; CHOICE Study Investigators. Ultra-low-dose continuous combined estradiol and norethisterone acetate: improved bleeding profile in postmenopausal women.Climacteric. 2008 Feb;11(1):63-73.

Bracke ME, Vanhoecke BW, Derycke L, Bolca S, Possemiers S, Heyerick A, Stevens CV, De Keukeleire D, Depypere HT, Verstraete W, Williams CA, McKenna ST, Tomar S, Sharma D, Prasad AK, DePass AL, Parmar VS. Plant polyphenolics as anti-invasive cancer agents. Anticancer Agents Med Chem. 2008 Feb;8(2):171-85.

Kenemans P, Bundred NJ, Foidart JM, Kubista E, von Schoultz B, Sismondi P, Vassilopoulou-Sellin R, Yip CH, Egberts J, Mol-Arts M, Mulder R, van Os S, Beckmann MW. Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial. LIBERATE Study Group.Lancet Oncol. 2009 Feb;10(2):135-46.

Blondeel PN, Hijjawi J, Depypere H, Roche N, Van Landuyt K. Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Plast Reconstr Surg. 2009 Feb;123(2):455-62. Review.

Hamdi M, Sinove Y, Depypere H, Van Den Broucke R, Vakaet L, Cocquyt V, Villeirs G, Lambein C, Van Maele G. The role of oncoplastic surgery in breast cancer. Acta Chir Belg. 2008 Nov-Dec;108(6):666-72.

Blondeel PN, Hijjawi J, Depypere H, Roche N, Van Landuyt K. Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part II–Breast reconstruction after total mastectomy. Plast Reconstr Surg. 2009 Mar;123(3):794-805.

Blondeel PN, Hijjawi J, Depypere H, Roche N, Van Landuyt K. Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part III–reconstruction following breast conservative treatment.Plast Reconstr Surg. 2009 Jul;124(1):28-38.

D’haeseleer E, Depypere H, Claeys S, Van Borsel J, Van Lierde K. The menopause and the female larynx, clinical aspects and therapeutic options: a literature review.Maturitas. 2009; 20;64(1):27-32. Equal contribution of the First two authors.

Blondeel PN, Hijjawi J, Depypere H, Roche N, Van Landuyt K. Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part IV–aesthetic breast surgery.Plast Reconstr Surg. 2009 Aug;124(2):372-82.

Bolca S, Wyns C, Possemiers S, Depypere H, De Keukeleire D, Bracke M, Verstraete W,Heyerick A. Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents.J Nutr. 2009; 139(12):2293-300.

Samsioe G, Hruska J; CHOICE Study Investigators. Optimal tolerability of ultra-low-dose continuous combined 17beta-estradiol and norethisterone acetate: laboratory and safety results. Climacteric. 2010 Feb;13(1):34-44. doi: 10.3109/13697130903480706

Bolca S, Urpi-Sarda M, Blondeel P, Roche N, Vanhaecke L, Possemiers S, Al-Maharik N, Botting N, De Keukeleire D, Bracke M, Heyerick A, Manach C & Depypere H (2010) Disposition of soy isoflavones in normal breast tissue. American Journal of Clinical Nutrition, 91:976-84.

Bolca S, Li J, Nikolic D, Roche N, Blondeel P, Possemiers S, De Keukeleire D, Bracke M, Heyerick A, van Breemen RB, Depypere H. Disposition of hop prenylflavonoids in human breast tissue. Mol Nutr Food Res. 2010 Jul;54 Suppl 2:S284-94.

Van Calster B, Van Ginderachter J, Vlasselaer J, Van de Putte G, Berteloot P, Timmerman D, Depypere H, Blomme C, Vlaemynck G, De Jonge E, Van den Broecke R, Vergote I, Amant F, Van Huffel S, Neven P. Uterine and quality of life changes in postmenopausal women with an asymptomatic tamoxifen-thickened endometrium randomized to continuation of tamoxifen or switching to anastrozole. Menopause. 2011 Feb;18(2):224-229.

D’haeseleer E, Depypere H, Claeys S, Wuyts FL, Baudonck N, Van Lierde KM.
Vocal Characteristics of Middle-Aged Premenopausal Women.J Voice. 2011; 25: 360-366.

Depypere HT, Hillard T, Erkkola R, Lukkari-Lax E, Kunz M, Rautiainen P, Schram JH. A 60-month non-comparative study on bleeding profiles with the levonorgestrel intrauterine system from the late transition period to estrogen supplemented menopause. Eur J Obstet Gynecol Reprod Biol. 2010 Dec;153(2):176-80.

D’haeseleer E, Depypere H, Claeys S, Wuyts FL, De Ley S, Van Lierde KM. The impact of menopause on vocal quality. Menopause. 2011;18:267-272. Oct 27.

D’haeseleer, E., Depypere, H., Claeys, S., Van Lierde, K.M. The relation between Body Mass Index and Speaking Fundamental Frequency in Pre- and Postmenopausal Women. Menopause 2011; 18(7): 754-8.

D’haeseleer, E., Depypere, H., Claeys, S. Van Lierde, K.M. Nasal resonance in middle aged women: a multiparameter approach. Annals of Otology, rhinology & laryngology 2011; 120(9): 575-580.

Derijcke L., Stove, C., Vercoutter-Edouart, A.-S., De Wever, O., Dollé, L., Colpaert, N., Depypere, H., Michalski, J.-C. and Bracke, M.: The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells, Int. J. Dev. Biol., 55, 835-840, 2011.

D’haeseleer E, Depypere H, Claeys S, Van Lierde K. The impact of menopause and hormone therapy on nasal resonance. Logoped Phoniatr Vocol. 2012 Jul;37(2):69-74. doi: 10.3109/14015439.2012.660501

D’haeseleer E, Depypere H, Claeys S, Baudonck N, Van Lierde K. The impact of hormone therapy on vocal quality in postmenopausal women. J Voice. 2012 Sep;26(5):671.e1-7. doi: 10.1016/j.jvoice.2011.11.011

Rees M, Pérez-López FR, Ceasu I, Depypere H, Erel T, Lambrinoudaki I, Schenck-Gustafsson K, Simoncini T, van der Schouw Y, Tremollieres F; EMAS. EMAS clinical guide: low-dose vaginal estrogens for postmenopausal vaginal atrophy. Maturitas. 2012 Oct;73(2):171-4. doi: 10.1016/j.maturitas.2012.06.009

Lambrinoudaki I, Ceasu I, Depypere H, Erel T, Rees M, Schenck-Gustafsson K, Simoncini T, Tremollieres F, van der Schouw YT, Pérez-López FR. EMAS position statement: Diet and health in midlife and beyond. Maturitas. 2013 Jan;74(1):99-104. doi: 0.1016/j.maturitas.2012.10.019

Pérez-López FR, Ceausu I, Depypere H, Erel CT, Lambrinoudaki I, Rees M, Schenck-Gustafsson K, Tremollieres F, van der Schouw YT, Simoncini T. EMAS clinical guide: Vulvar lichen sclerosus in peri and postmenopausal women. Maturitas. 2013 Jan 3. doi:pii: S0378-5122(12)00406-9. 10.1016/j.maturitas.2012.12.006

Dreisler E, Poulsen LG, Antonsen SL, Ceausu I, Depypere H, Erel CT, Lambrinoudaki I, Pérez-López FR, Simoncini T, Tremollieres F, Rees M, Ulrich LG. EMAS clinical guide: Assessment of the endometrium in peri and postmenopausal women. Maturitas. 2013 Jun;75(2):181-90. doi: 10.1016/j.maturitas.2013.03.011

Davies C, Pan H, Godwin J, Gray R, Arriagada R, Raina V, Abraham M, Medeiros Alencar VH, Badran A, Bonfill X, Bradbury J, Clarke M, Collins R, Davis SR, Delmestri A, Forbes JF, Haddad P, Hou MF, Inbar M, Khaled H, Kielanowska J, Kwan WH, Mathew BS, Mittra I, Müller B, Nicolucci A, Peralta O, Pernas F, Petruzelka L, Pienkowski T, Radhika R, Rajan B, Rubach MT, Tort S, Urrútia G, Valentini M, Wang Y, Peto R; Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) Collaborative Group. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial. Lancet. 2013 Mar 9;381(9869):805-16. Erratum in: Lancet. 2013 Mar 9;381(9869):804.

Mintziori G, Lambrinoudaki I, Kolibianakis EM, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw Y, Simoncini T, Tremollieres F, Tarlatzis BC, Rees M, Goulis DG. EMAS position statement: Late parenthood. Maturitas. 2013 Oct;76(2):200-4. doi: 10.1016/j.maturitas.2013.07.008

D’haeseleer E, Depypere H, Van Lierde K. Comparison of Speaking Fundamental Frequency between Premenopausal Women and Postmenopausal Women with and without Hormone Therapy. Folia Phoniatr Logop. 2013;65(2):78-83. doi: 10.1159/000350405

Mintziori G, Lambrinoudaki I, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw YT, Simoncini T, Tremollieres F, Tarlatzis BC, Rees M, Goulis DG. EMAS position statement: Fertility preservation. Maturitas. 2014 Jan;77(1):85-9. doi: 10.1016/j.maturitas.2013.10.010
Depypere HT, Comhaire FH. Herbal preparations for the menopause: Beyond isoflavones and black cohosh. Maturitas. 2014 Feb;77(2):191-4. doi: 10.1016/j.maturitas.2013.11.001
Brockie J, Lambrinoudaki I, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw YT, Simoncini T, Tremollieres F, Rees M; European Menopause and Andropause Society. EMAS position statement: Menopause for medical students. Maturitas. 2014 May;78(1):67-9. doi: 10.1016/j.maturitas.2014.02.007

Triantafyllopoulos IK, Lambropoulou-Adamidou K, Nacopoulos CC, Papaioannou NA, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw YT, Simoncini T, Tremollieres F, Rees M, Lambrinoudaki I; European Menopause and Andropause Society. EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture. Maturitas. 2014 Jun;78(2):131-7. doi: 10.1016/j.maturitas.2014.03.002

Pérez-López FR, Ornat L, Ceausu I, Depypere H, Erel CT, Lambrinoudaki I, Schenck-Gustafsson K, Simoncini T, Tremollieres F, Rees M. EMAS position statement: management of uterine fibroids. Maturitas. 2014 Sep;79(1):106-16. doi: 10.1016/j.maturitas.2014.06.002

Depypere H, Desreux J, Pérez-López FR, Ceausu I, Erel CT, Lambrinoudaki I, Schenck-Gustafsson K, van der Schouw YT, Simoncini T, Tremollieres F, Rees M. EMAS position statement: individualized breast cancer screening versus population-based mammography screening programmes. Maturitas. 2014 Dec;79(4):481-6. doi: 10.1016/j.maturitas.2014.09.002

Depypere H, Inki P. The levonorgestrel-releasing intrauterine system for endometrial protection during estrogen replacement therapy: a clinical review. Climacteric. 2015 Jan 2:1-32.

Gaspard U, Verguts J, Simon P, Depypere H, Merckx M, Loquet P, Walravens F, Firquet A, Poppe W, Leunen M, Donders G, Squifflet J, Grandjean P. The use of intrauterine device in nulliparous over 18 years: a Belgian consensus. J Pharm Belg. 2014 Dec;(4):28-35. French.

Comhaire FH, Depypere HT. Hormones, herbal preparations and nutriceuticals for a better life after the menopause: part I. Climacteric. 2015 Jun;18(3):358-63. doi: 10.3109/13697137.2014.985645

Comhaire FH, Depypere HT. Hormones, herbal preparations and nutriceuticals for a better life after the menopause: part II. Climacteric. 2015 Jun;18(3):364-71. doi: 10.3109/13697137.2014.985646

Vertriest C, Berardi G, Tomassini F, Vanden Broucke R, Depypere H, Cocquyt V, Denys H, Van Belle S, Troisi RI. Resection of single metachronous liver metastases from breast cancer stage I-II yield excellent overall and disease-free survival. Single center experience and review of the literature. Dig Surg. 2015;32(1):52-9. doi: 10.1159/000375132

Depypere H, Desreux J, Rees M; EMAS board. Response to the question: How does information reduce psychological impact? Maturitas. 2015 Apr;80(4):442. doi: 10.1016/j.maturitas.2015.01.006

Depypere HT, Bolca S, Bracke M, Delanghe J, Comhaire F, Blondeel P. The serum estradiol concentration is the main determinant of the estradiol concentration in normal breast tissue.
Maturitas. 2015 May;81(1):42-5. doi: 10.1016/j.maturitas.2015.01.014

Neves-E-Castro M, Birkhauser M, Samsioe G, Lambrinoudaki I, Palacios S, Borrego RS, Llaneza P, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw YT, Simoncini T, Tremollieres F, Rees M. EMAS position statement: The ten point guide to the integral management of menopausal health. Maturitas. 2015 May;81(1):88-92. doi: 10.1016/j.maturitas.2015.02.003

Depypere H. Answer to the comment by Per Eystein Lønning on “The serum estradiol concentration is the main determinant of the estradiol concentration in normal breast tissue”.
Maturitas. 2015 Jun;81(2):328. doi: 10.1016/j.maturitas.2015.03.023

Mintziori G, Lambrinoudaki I, Goulis DG, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, Simoncini T, Tremollieres F, Rees M. EMAS position statement: Non-hormonal management of menopausal vasomotor symptoms. Maturitas. 2015 Jul;81(3):410-3. doi: 10.1016/j.maturitas.2015.04.009

Mintziori G, Goulis DG, Lambrinoudaki I, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, Simoncini T, Tremollieres F, Rees M. Non-hormonal management of menopausal vasomotor symptoms: Psychosocial interventions. Maturitas. 2015 Dec;82(4):444-5. doi: 10.1016/j.maturitas.2015.08.011

Dimopoulou C, Ceausu I, Depypere H, Lambrinoudaki I, Mueck A, Pérez-López FR, Rees M, van der Schouw YT, Senturk LM, Simonsini T, Stevenson JC, Stute P, Goulis DG. EMAS position statement: Testosterone replacement therapy in the aging male‏. Maturitas. 2016 Feb;84:94-9. doi: 10.1016/j.maturitas.2015.11.003

Herman Depypere (UGent) , Anne Vierin (UGent) , Steven Weyers (UGent) and Anne Sieben (UGent). Alzheimer’s disease, apolipoprotein E and hormone replacement therapy. MATURITAS. 2016: 94. p.98-105.
Petra Stute, Iuliana Ceausu, Herman Depypere (UGent) , Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Yvonne T van der Schouw, Levent M Senturk, Tommaso Simoncini, John C Stevenson, et al. A model of care for healthy menopause and ageing : EMAS position statement. MATURITAS. 2016: 92. p.1-6.

Filip Stillaert (UGent) , Casper Sommeling, Salvatore D’Arpa (UGent) , David Creytens (UGent) , Koenraad Van Landuyt (UGent) ,Herman Depypere (UGent) , Rudy Van den Broecke (UGent) , Stan Monstrey (UGent) , Phillip Blondeel (UGent) and Wayne A Morrison. Intratissular expansion-mediated, serial fat grafting : a step-by-step working algorithm to achieve 3D biological harmony in autologous breast reconstruction. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY. 2016 69(12). p.1579-1587.

Herman Depypere (UGent) , A Pintiaux, J Desreux, M Hendrickx, P Neven, E Marchowicz, V Albert, V Leclercq, S Van den Branden and S Rozenberg. Coping with menopausal symptoms: an internet survey of Belgian postmenopausal women. Maturitas . 2016. 90. p.24-30.

Amanda Griffiths, Iuliana Ceausu, Herman Depypere (UGent) , Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Yvonne T van der Schouw, Levent M Senturk, Tommaso Simoncini, John C Stevenson, et al. EMAS recommendations for conditions in the workplace for menopausal women. MATURITAS. 2016: 85. p.79-81.

Elke Bruneel (UGent) , Heleen Maes, Marie-Astrid Denys (UGent) , Herman Depypere (UGent) and Karel Everaert (UGent). Nocturia and hormone replacement therapy : do we change the bladder or the kidney? ICS 2016.

Louis Coussement (UGent) , Selin Bolca (UGent) , Wim Van Criekinge (UGent) , Geert Trooskens (UGent) , Klaas Mensaert(UGent) , Katrien Poels, Nathalie Roche (UGent) , Phillip Blondeel (UGent) , Lode Godderis, Herman Depypere (UGent) , et al. Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure. SCIENTIFIC REPORTS. 2018.

Christel Monten (UGent) , Liv Veldeman (UGent) , Katrien Vandecasteele (UGent) , Ana Maria Luiza Olteanu (UGent) , Werner De Gersem (UGent) , Tom Vercauteren (UGent) , THOMAS MULLIEZ, Rudy Van den Broecke (UGent) , Herman Depypere (UGent) ,Wilfried De Neve (UGent) , et al. External partial breast irradiation in prone position : how to improve accuracy? ACTA ONCOLOGICA. 2018. 57(10). p.1339-1345

C. E. Sommeling, Koenraad Van Landuyt (UGent) , Herman Depypere (UGent) , Rudy Van den Broecke (UGent) , Stan Monstrey(UGent) , Phillip Blondeel (UGent) , W. A. Morrison and Filip Stillaert (UGent). Composite breast reconstruction: Implant-based breast reconstruction with adjunctive lipofilling. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY. 2017. 70(8). p.1051-1058.

Frederique Van de Velde (UGent) , Anneloor Dierickx, Herman Depypere (UGent) , Joris Delanghe (UGent) , Jean Kaufman (UGent)and Bruno Lapauw (UGent). Reproducibility and least significant differences of oral glucose tolerance test-derived parameters in a postmenopausal population without diabetes. DIABETES & METABOLISM. 2017 43(5). p.484-487.

Florence A Trémollieres, Luliana Ceausu, Herman Depypere (UGent) , Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Yvonne T van der Schouw, Levent M Senturk, Tommaso Simoncini, John C Stevenson, et al. Osteoporosis management in patients with breast cancer : EMAS position statement. MATURITAS. 2017;95. p.65-71.

Faustino R Pérez-López, Iuliana Ceausu, Herman Depypere (UGent) , Sean Kehoe, Irene Lambrinoudaki, Alfred Mueck, Levent M Senturk, Tommaso Simoncini, John C Stevenson, Petra Stute, et al. Interventions to reduce the risk of ovarian and fallopian tube cancer : a European Menopause and Andropause Society position statement. MATURITAS. 2017: 100. p.86-91

Panagiotis Anagnostis, Stavroula A Paschou, Gesthimani Mintziori, Iuliana Ceausu, Herman Depypere (UGent) , Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Margaret Rees, Levent M Senturk, et al. Bisphosphonates or denosumab discontinuation and risk of fractures : response to the letter by Anastasilakis et al. MATURITAS. 2017:102. p.76-77.

Panagiotis Anagnostis, Stavroula A Paschou, Gesthimani Mintziori, Iuliana Ceausu, Herman Depypere (UGent) , Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Margaret Rees, Levent M Senturk, et al. Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis : EMAS position statement. MATURITAS. 2017:101. p.23-30.
Pieter Deseyne (UGent) , Bruno Speleers (UGent) , Wilfried De Neve (UGent) , Bert Boute (UGent) , Leen Paelinck (UGent) , Tom Van Hoof (UGent) , Joris Van de Velde (UGent) , Annick Van Greveling (UGent) , Christel Monten (UGent) , Giselle Post (UGent) , et al. Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer. (2017) RADIATION ONCOLOGY. 12.

Maria Teresa Ferretti, Maria Florencia Iulita, Enrica Cavedo, Patrizia Andrea Chiesa, Annemarie Schumacher Dimech, Antonella Santuccione Chadha, Francesca Baracchi, Helene Girouard, Sabina Misoch, Ezio Giacobini, Herman Depypere, Harald Hampel. Sex differences in Alzheimer disease: the gateway to precision medicine. NATURE REVIEWS NEUROLOGY 2018 14(8). p.457-469

Harald Hampel, Andrea Vergallo, Filippo Sean Giorgi, Seung Hyun Kim, Herman Depypere (UGent) , Manuela Graziani, Amira Saidi, Robert Nistico and Simone Lista. Precision medicine and drug development in Alzheimer’s disease : the importance of sexual dimorphism and patient stratification. Precision medicine and drug development in Alzheimer’s disease : the importance of sexual dimorphism and patient stratification. FRONTIERS IN NEUROENDOCRINOLOGY 2018 50. p.31-51

Andrea Vergallo, Rene-Sosata Bun, Nicola Toschi, Filippo Baldacci, Henrik Zetterberg, Kaj Blennow, Enrica Cavedo, Foudil Lamari, Marie-Odile Habert, Bruno Dubois, Floris Roberto, Garaci Francesco, Lista Simone, Herman Depypere, Harald Hampel. Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer’s disease biomarkers. ALZHEIMERS & DEMENTIA 2018 14(12). p.1623-1631

Enrica Cavedo, Patrizia A. Chiesa, Marion Houot, Maria Teresa Ferretti, Michel J. Grothe, Stefan J. Teipel, Simone Lista, Marie-Odile Habert, Marie-Claude Potier, Bruno Dubois, Floris Roberto, Garaci Francesco, Lista Simone, Herman Depypere, Harald Hampel. Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer’s disease in cognitively normal older adults with subjective memory complaints. ALZHEIMERS & DEMENTIA 2018. 14(9). p.1204-1215.

Vergallo A, Houot M, Cavedo E, Lemercier P, Vanmechelen E, De Vos A, Habert MO, Potier MC, Dubois B, Lista S, Hampel H; INSIGHT-preAD study group. Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD. Alzheimer Precision Medicine Initiative (APMI). Alzheimers Dement. 2019

Depypere H, Timmerman D, Donders G, Sieprath P, Ramael S, Combalbert J, Hoveyda HR, Fraser GL. Treatment of Menopausal Vasomotor Symptoms With Fezolinetant, a Neurokinin 3 Receptor Antagonist: A Phase 2a Trial. J Clin Endocrinol Metab. 2019 Dec 1;104(12):5893-5905. doi: 10.1210/jc.2019-00677.

Depypere HT, Stanczyk FZ, Croubels S, Blondeel PN, Roche NA, Depypere BP, Vanhaecke L. Breast levonorgestrel concentrations in women using a levonorgestrel-releasing intrauterine system. Contraception. 2019 Oct;100(4):299-301.

Chiesa PA, Cavedo E, Vergallo A, Lista S, Potier MC, Habert MO, Dubois B, Thiebaut de Schotten M, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer’s disease. Alzheimers Dement. 2019 Jul;15(7):940-950.

Vergallo A, Mégret L, Lista S, Cavedo E, Zetterberg H, Blennow K, Vanmechelen E, De Vos A, Habert MO, Potier MC, Dubois B, Neri C, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer’s disease.
Alzheimers Dement. 2019 Jun;15(6):764-775.

Jonckheere S, Depypere H, Standaert C. Breast Lymphoma: Teaching point: Primary breast lymphoma is a rare disease, especially in males, but should be considered in the differential diagnosis of a breast mass because of the different treatment and prognosis.
J Belg Soc Radiol. 2019 Apr 9;103(1):26. doi: 10.5334/jbsr.1769.

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. Genazzani A, Panay N, Simoncini T, Depypere H, Mueck A, Egarter C, Biglia N, Fait T, Birkhaeuser M, Skouby SO, Brincat M, Goldstein S, Ruan X, Celis-Gonzales C, Palacios S. Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. Gynecol Endocrinol. 2020 Mar;36(3):190-196.
Depypere B, Herregods S, Denolf J, Kerkhove LP, Mainil L, Vyncke T, Blondeel P, Depypere H. 20 Years of DIEAP Flap Breast Reconstruction: A Big Data Analysis. Sci Rep. 2020 Jan 24;10(1):1398. doi: 10.1038/s41598-020-58292-0.

Depypere H, Dierickx A, Van de Velde F, F Stanczyk, Ottoy L, Delanghe J, Lapauw B.. A randomized trial on the effect of oral combined estradiol and drospirenone on glucose and insulin metabolism in healthy menopausal women with a normal OGTT. Maturitas 2020 138:36-41.

Cavedo E, Lista S, Houot M, Vergallo A, Grothe MJ, Teipel S, Zetterberg H, Blennow K, Habert MO, Potier MC, Dubois B, Hampel H; INSIGHT-preAD Study Group, Alzheimer Precision Medicine Initiative. Plasma tau correlates with basal forebrain atrophy rates in people at risk for Alzheimer disease. Neurology. 2020 Jan 7;94(1):e30-e41.

Herman Depypere, Christopher Lademacher, Emad Siddiqui, Graeme L Fraser. Fezolinetant in the treatment of vasomotor symptoms associated with menopause. Expert Opinion On Investigational Drugs 2021: in press (impact factor 5,08).

Depypere H, Su Y, Dang N, Poppe B, Stanczyk FZ, Janssens J, Russo J. prolonged recombinant pregnancy hormone use for breast cancer prevention in BRCA1 and 2 mutation carriers. European J of cancer prevention 2021: open access available online

Pauwaert K, Goessaert AS, Ghijselings L, Bower W, Depypere H, Everaert K. Characterizing nocturia among Belgian healthy postmenopausal women : prevalence, bother, etiology and possible risk factors for developing nocturia. MATURITAS. 2021 143. p.41-46.

Depypere H1, Vergallo A2*, Lemercier P2*, Lista S2, Benedet AL3 Ashton NJ3,4,5,6, Cavedo E, Zetterberg H3, 7, 8, 9, 10, Blennow K3,7, Vanmechelen E11, Hampel H2; the Neurodegeneration Precision Medicine Initiative (NPMI): Menopause Hormone Therapy significantly alters
Pathophysiological Biomarkers of Alzheimer’s Disease. ALZHEIMERS & DEMENTIA 2022, free of access.
Yanrong Su 1, Nhi M Dang 1, Herman Depypere 2, Julia Santucci-Pereira 1, Pedro J Gutiérrez-Díez 3, Joice Kanefsky 1, Jaak Ph Janssens 4, Jose Russo 1 Recombinant human chorionic gonadotropin induces signaling pathways towards cancer prevention in the breast of BRCA1/2 mutation carriers. European J of Cancer prevention, 2022, online free of access.